General Information

  • ID:  hor004278
  • Uniprot ID:  A0A1S4FE51
  • Protein name:  Tachykinin-related peptide
  • Gene name:  5568206
  • Organism:  Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
  • Family:  Tachykinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Stegomyia (subgenus), Aedes (genus), Aedini (tribe), Culicinae (subfamily), Culicidae (family), Culicoidea (superfamily), Culicomorpha (infraorder), Nematocera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  APSGFLGLR
  • Length:  9
  • Propeptide:  MNTIRIGTLVLLMLNIYFSYADPGVKSDVTKNIRDKRDHYYSEGVGNFYSNFNEPDNAITTVLPLLDTDGTSKVANDVPTDNDDGEDDALVSHSLDDEFHYFRPNPDSGVEGKLNYDWNNDDTNENRLDVRGKKNIPFYPLRLYPKRAPSGFLGLRGKKYYYNGAKRVPSGFTGMRGKKAFYDMNSSFDDNTNQLELTKDIHFDELLQRERAFLEELYRIHQIEQEISNNPSISTFQTSEKRAPSGFLGMRGKKATEDSSSNSETKRAPSGFLGLRGKRANIDDYIEGNKRTTFTSYFGMQGNKEPLILGSDKIYSQLNRMNWPVNDRLQMDRTPPKRVPNGFLGVRGKKWTDTIYDE
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A1S4FE51-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor004278_AF2.pdbhor004278_ESM.pdb

Physical Information

Mass: 105995 Formula: C42H68N12O11
Absent amino acids: CDEHIKMNQTVWY Common amino acids: GL
pI: 10.55 Basic residues: 1
Polar residues: 3 Hydrophobic residues: 4
Hydrophobicity: 50 Boman Index: -181
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 97.78
Instability Index: 7308.89 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  20163154
  • Title:  Neuropeptidomics of the Mosquito Aedes Aegypti